2014年6月26日星期四

the prevalence rate can make nothing of it.

June 25th news: yesterday, Shanghai Medical College of Fudan University from news: research group led by the Institute of State Key Laboratory of neurobiology, Dr. Sha Hongying, Professor Zhu Jianhong, Medical University Of Anhui professor Cao Yunxia in the United team, to explore the genetic mitochondrial diseases breakthrough progress has been made in. The team found that: ovum during meiosis, from egg capsule "small cell" -- the polar body, can effectively block the mitochondrial genetic disease. The related results published in leading academic journals "cell".Mitochondrial

experts, has its own set of DNA, and through the mother's eggs were passed on to the next generation. In the eggs of mitochondrial mutations, will involve the brain, muscle, heart and so on many an important part of the body, and then causes the maternal familial disease. At present, the mitochondrial genetic disease known cheap mlb jerseys to include: mitochondrial encephalomyopathy, mitochondrial encephalopathy, subacute necrotizing encephalomyelopathy etc.. Because the treatment is very limited, many patients can only rely on drugs to short-term remission of symptoms, not cure, a lot of survival of children with very short, almost not live to adulthood. Data show: USA mitochondrial cheap jerseys disease prevalence rate is about 1/5000, our country because of the lack of sample statistics, the prevalence rate can make nothing of it.

mitochondria by "cytoplasm" to maternal inheritance into the next generation, how to block the genetic, is always the key problem of scientists to contemplate. Research group led cheap nba jerseys by Dr. Sha Hongying, Professor Zhu Jianhong, has long been engaged in the study of nuclear reprogramming. Find them and cheapjerseys.us eggs "in the lab and be together morning and night" process: eggs, degradation of small cell "polar body" is particularly interesting, it "is located in the" egg envelope, which contained genetic material. The polar body this almost lost utility function, cheap nfl jerseys can become blocked the new technology of mitochondrial genetic?

group since the beginning of 2011, the biological characteristics of polar body as the starting point, instead of the genetic material in the cytoplasm genetic material in the polar body, studies on mitochondrial replacement in two different genetic backgrounds of the mice. The experimental results surprising: the first polar body replacement of the generation of mice, and its derivative two generation mice, the maximum extent to avoid the genetic heterogeneity of mitochondrial DNA. Research group also found that, the earlier the original nuclear transplantation, spindle compound transplantation, polar body has its obvious advantages, the potential value of clinical application. Zhu Jianhong said, research and further clarified the human cognition of the polar body biology, more hope in the clinical prevention of maternal inheritance of mitochondrial diseases.

Dr.

Sha Hongying said, although the animal model has been gratifying results, but to further application in the human, there is still a long way to go in the future. The next stage will strengthen cooperation with the clinical research team, and strive to transform the achievement to the clinical, provide effective intervention techniques for mitochondrial disease.

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